This is an obvious rejection.
He has no reason to assist Orochimaru in completing those inhumane human experiments.
In any case, the experiments conducted by the other party must be those that violate the moral and ethical codes, the Forbidden Research.
Like the evil Forbidden Technique that manipulates human souls and life and death, such as Impure World Reincarnation.
Being a member of the same organization, he could not stop the other party, but he would also not aid the enemy.
If given the chance, he would even want to kill Orochimaru, to end his life and remove this major threat for Konoha.
Letting a person like this live, the Ninja Realm is bound to face many problems sooner or later.
Saying this, Itachi turned around, intending to leave.
Suddenly, his body stiffened.
A blue Giant Snake appeared out of nowhere, coiling around his body. The blue snake contracted its body, its restraining power was immense, an ordinary person's bones would likely be crushed completely.
Orochimaru stood behind Itachi, letting out a sinister laugh in Itachi's ear: "Don't be so cold, Itachi-kun, you are an important material I greatly admire. If you are willing to help me, I might be able to help your Sharingan progress even further. This way, your chances of killing Uchiha Ruri would be even greater."
What? Itachi was deeply shocked.
Why... would Orochimaru know about Madara's plan?
Could it be that Madara also had a connection with Orochimaru?
Killing Uchiha Ruri, this should be a pact between himself and Madara. Initially, he thought that only three people knew in the organization, besides himself and Madara, only Leader Nagato knew about this matter.
Now, Orochimaru casually saying this made him have to reassess the complex interpersonal relationships within the organization.
Since Orochimaru knows about this, it means, there must be dealings between him and Madara.
Was it before he joined, or just recently that he contacted Madara? Itachi couldn't tell.
"I've fought against Hyuga Ayane. The power of those Byakugan eyes is unbelievably terrifying. Uchiha Ruri's strength is akin to hers. Compared to her, with your current capabilities, you can't cooperate with the organization to eliminate this formidable enemy in the future. Participating in my experiments is your only choice."
Orochimaru continued with a manipulative voice, laughing.
"Sounds pleasant, you want to use the Forbidden Techniques you've developed to gain the power of the Uchiha Clan, right."
Itachi looked straight ahead, speaking coldly.
"How could that be, the Leader warned members not to kill each other. I sincerely invite Itachi-kun to join my experiments. The power of the Mangekyo Sharingan is just irresistible."
Saying this, Orochimaru opened his mouth, revealing snake-like fangs filled with venom, fiercely biting towards Itachi's neck.
Poof!
The blue Giant Snake coiled around Itachi was cut into several pieces, blood splattered everywhere, and Itachi disappeared from there, standing a few meters away with a blood-stained Kunai in hand.
Seeing his attack miss, Orochimaru was not surprised. If Itachi could be subdued that easily, then a prodigy capable of massacring his clan would be too disappointing.
"Many Hidden Shadow Snake Hands!"
A multitude of thick giant snakes surged out from Orochimaru's sleeve, blocking all of Itachi's escape routes.
"Fire Style: Great Fireball Jutsu!"
Without seeing Itachi making any hand seals, a huge and fierce fireball sprayed from Itachi's mouth, its power exceeding that of an ordinary Giant Fireball, turning several thick giant snakes into ash.
This wasn't the end, the fireball continued to attack Orochimaru's body.
Orochimaru avoided the Great Fireball's offensive without hesitation, watching intently at Itachi's pair of Sharingan emitting a scarlet glow, while licking his tongue, his eyes filled with excitement and anticipation.
Truly different from the average Uchiha clansman.
Just based on his speed in releasing ninja techniques, even he, a genius among the Sannin, found it difficult to match.
"Then how about this move?"
Avoiding the Great Fireball, Orochimaru suddenly crouched on the ground, mouth wide open, a terrifying burst of Chakra erupted from his body.
"Array of Ten Thousand Snakes!"
Endless snakes formed a sea of snakes, engulfing everything in front of them, including the dilapidated temple behind Itachi, also swallowed by the sea of snakes.
Orochimaru slowly stood up from the ground, the surrounding scene suddenly underwent a strange transformation, surprising Orochimaru.
He saw the sea of snakes disappear, the sky stained with blood, countless pitch-black crows cawing incessantly, flying to the sky, dropping a large mass of black feathers, falling on Orochimaru and the surroundings.
"Body..."
Orochimaru's eyes were filled with horror.
Huge and solid iron nails pierced through his body, rendering him unable to move.
The air in front suddenly twisted, and Itachi's body appeared there, his scarlet Sharingan eyes coldly staring at Orochimaru.
"I actually fell into an Illusion Technique..."
Orochimaru gritted his teeth, glaring at Itachi, finding it hard to believe that someone like him, a member of the Sannin, would fall for such a trivial trick.
In other words, a mere thirteen-year-old kid, in the field of Illusion Techniques, actually surpassed him?
Impossible.
Unless it's the Mangekyo Sharingan, such Sharingan-level Illusion Techniques could be broken easily. However, the cruel scene in front of him made Orochimaru have to believe this fact.
"Like Danzo, you also covet the power of the Uchiha Clan, greedy yet pitiful."
Itachi said this.
"A kid being toyed by Danzo, also wants to lecture me?"